Opioids potentiate electrical transmission at mixed synapses on the Mauthner cell.

@article{Cachope2015OpioidsPE,
  title={Opioids potentiate electrical transmission at mixed synapses on the Mauthner cell.},
  author={Roger Cachope and Alberto E Pereda},
  journal={Journal of neurophysiology},
  year={2015},
  volume={114 1},
  pages={689-97}
}
Opioid receptors were shown to modulate a variety of cellular processes in the vertebrate central nervous system, including synaptic transmission. While the effects of opioid receptors on chemically mediated transmission have been extensively investigated, little is known of their actions on gap junction-mediated electrical synapses. Here we report that pharmacological activation of mu-opioid receptors led to a long-term enhancement of electrical (and glutamatergic) transmission at identifiable… CONTINUE READING