Opioids modulate constitutive B-lymphocyte secretion.

  title={Opioids modulate constitutive B-lymphocyte secretion.},
  author={D. Vassou and E. Bakogeorgou and M. Kampa and H. Dimitriou and Anastassia Hatzoglou and E. Castanas},
  journal={International immunopharmacology},
  volume={8 5},
  • D. Vassou, E. Bakogeorgou, +3 authors E. Castanas
  • Published 2008
  • Medicine, Biology
  • International immunopharmacology
  • The opioid system plays a major role in immunomodulation, while its action on cells of the immune system may be opioid receptor-mediated or not. Opioid effects on B-lymphocytes are considered as indirect, attributed to an interplay between distinct cell populations. The aim of the present study was to investigate whether opioid agonists (morphine, alpha(S1)-casomorphin and ethylketocyclazocine) may have a direct action on the secretion of antibodies and cytokines by multiple myeloma-derived… CONTINUE READING
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