Opioids in the Systemic Hemodynamic and Renal Responses to Stress in Conscious Spontaneously Hypertensive Rats

@inproceedings{Kapusta2005OpioidsIT,
  title={Opioids in the Systemic Hemodynamic and Renal Responses to Stress in Conscious Spontaneously Hypertensive Rats},
  author={Daniel R. Kapusta and Susan Y. Jones and Gerald F Dibona},
  year={2005}
}
Endogenous opioid peptides have been implicated in the regulation of cardiovascular and renal function. We tested this hypothesis by examining whether the opioid antagonist naloxone alters the cardiovascular or renal responses produced by environmental stress (air stress) in conscious spontaneously hypertensive rats (SHR). Before naloxone administration, air stress produced significant increases in heart rate, mean arterial pressure, and renal sympathetic nerve activity, and it caused a… CONTINUE READING