Opioids for the management of breakthrough (episodic) pain in cancer patients.

  title={Opioids for the management of breakthrough (episodic) pain in cancer patients.},
  author={Giovambattista Zeppetella and Marlise de Castro Ribeiro},
  journal={The Cochrane database of systematic reviews},
BACKGROUND Breakthrough pain is a transient increase in pain intensity over background pain. It is a common and distinct component of cancer pain that can have a negative impact for both the patient and carers' quality of life. Breakthrough pain is usually related to background pain and is typically of rapid onset, severe in intensity, and generally self-limiting with an average duration of 30 minutes. At present the current approach to managing breakthrough pain is using supplemental analgesia… CONTINUE READING

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