Opioidergic, serotonergic, and dopaminergic manipulations and rats' intake of a sweetened alcoholic beverage.

@article{Hubbell1991OpioidergicSA,
  title={Opioidergic, serotonergic, and dopaminergic manipulations and rats' intake of a sweetened alcoholic beverage.},
  author={C. L. Hubbell and S. H. Marglin and S. Spitalnic and M. Abelson and K. Wild and L. D. Reid},
  journal={Alcohol},
  year={1991},
  volume={8 5},
  pages={
          355-67
        }
}
Groups of rats were maintained on a daily regimen of 22 h of water deprivation followed by a 2-h opportunity to take either water or a sweetened ethanol solution (ES). In one experiment, it was shown that previous morphine (M) dependence had no effect on initial daily intakes of fluids. After stable ES intakes were achieved, a variety of pharmacological manipulations were assessed for their effects on intake of the ES. Nalmefene, an opioid antagonist, dose-relatedly decreased intakes of ES, and… Expand
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