Opioid treatment for acute and chronic pain in patients with sickle cell disease

@article{Carroll2020OpioidTF,
  title={Opioid treatment for acute and chronic pain in patients with sickle cell disease},
  author={C. P. Carroll},
  journal={Neuroscience Letters},
  year={2020},
  volume={714}
}
Sickle cell disease is a uniquely complex painful disease, with lifelong episodes of unpredictable acute pain and superimposed chronic pain in adulthood. Both painful crises and chronic pain in sickle cell disease lack strong objective pathological correlates and their mechanisms are poorly understood. Opioids have emerged as the standard of care for severe acute pain in sickle cell disease and many patients with chronic pain are maintained on chronic opioid therapy. The strong association… Expand
4 Citations
Pain Experiences of Adults With Sickle Cell Disease and Hematopoietic Stem Cell Transplantation: A Qualitative Study.
TLDR
Clinicians should use a patient-centered approach, integrating non-opioid approaches into pain management, particularly psychosocial support as transplant for SCD becomes increasingly available, to improve health care delivery and overall patient experiences. Expand
Patient with Sickle Cell Disease
TLDR
The goal of this chapter is to provide an overview of the disease processes that drive the clinical manifestations of pain in sickle cell disease and draw attention to the distinct elements of managing the disease. Expand
A Pilot Study of the Acceptability, Feasibility and Safety of Yoga for Chronic Pain in Sickle Cell Disease.
TLDR
Patients with SCD and chronic pain overall have a positive opinion of yoga, but there are challenges with recruitment and retention of participants in a clinical trial of Yoga, and barriers to feasibility of an in-person group yoga intervention. Expand
Buprenorphine for chronic pain in a pediatric patient with sickle-cell disease.

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