Opioid regulation of AP-1 DNA-binding activity in NG108-15 cells under conditions of opioid-receptor adaptation.

@article{Tencheva1997OpioidRO,
  title={Opioid regulation of AP-1 DNA-binding activity in NG108-15 cells under conditions of opioid-receptor adaptation.},
  author={Zvetanka S Tencheva and Mariana M Belcheva and Adriana A Velichkova and E G Lissichkova and Carmine J. Coscia},
  journal={Brain research. Molecular brain research},
  year={1997},
  volume={48 1},
  pages={156-8}
}
Opioid-receptor adaptation may lead to changes in transcriptional regulation by sequence-specific DNA-binding proteins. Gel-shift assays of nuclear extracts from NG108-15 cells revealed that an increase of AP-1 DNA-binding activity ensues under conditions previously established to induce down- or up-regulation of delta-opioid receptors.