Opioid receptors.

  title={Opioid receptors.},
  author={Maria Waldhoer and Selena E Bartlett and Jennifer L. Whistler},
  journal={Annual review of biochemistry},
Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones. Opioid receptors are particularly intriguing members of this receptor family. They are activated both by endogenously produced opioid peptides and by exogenously administered opiate compounds, some of which are not only among the most… 

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