Opioid receptors and their interacting proteins

  title={Opioid receptors and their interacting proteins},
  author={Graeme Milligan},
  journal={NeuroMolecular Medicine},
The opioid receptors are among the most highly studied members of the family of G protein-coupled receptors. As for many other members of this family, recent studies have indicated that they do not exist in isolation but are able to interact with a substantial range of other polypeptides. Such interactions can alter the effectiveness of agonist-mediated cell signalling, determine the signals generated, alter the intracellular trafficking routes of the receptors and potentially determine… CONTINUE READING

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Identification of a novel family of G protein-coupled receptor associated sorting proteins

F. Simonin, P. Karcher, J J.Boeuf, A. Matifas, B. L. Kieffer
J. Neurochem • 2004
View 6 Excerpts
Highly Influenced

Interaction between the mu opioid receptor and filamin A is involved in receptor regulation and trafficking

I. Onoprishvili, M L.Andria, +3 authors E J.Simon
Mol. Pharmacol • 2003
View 5 Excerpts
Highly Influenced

Calmodulin binding to G protein-coupling domain of opioid receptors.

The Journal of biological chemistry • 1999
View 5 Excerpts
Highly Influenced

Opioid receptor regulation

NeuroMolecular Medicine • 2007
View 2 Excerpts
Highly Influenced

Dopamine D2 and D3 receptors are linked to the actin cytoskeleton via interaction with filamin A.

Proceedings of the National Academy of Sciences of the United States of America • 2001
View 4 Excerpts
Highly Influenced

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