Opioid receptors and opioid peptide-producing leukocytes in inflammatory pain – Basic and therapeutic aspects
@article{BuschDienstfertig2010OpioidRA, title={Opioid receptors and opioid peptide-producing leukocytes in inflammatory pain – Basic and therapeutic aspects}, author={Melanie Busch-Dienstfertig and Christoph Stein}, journal={Brain, Behavior, and Immunity}, year={2010}, volume={24}, pages={683-694} }
74 Citations
Mechanisms of Expression and Release of Endogenous Opioids in Peripheral Tissues
- BiologyNeurophysiology
- 2016
There are reasons to believe that the clinical use of peripherally acting opioids can help one to substantially avoid the negative side effects caused by the action of conventional analgesics (opioids and anticonvulsants).
Modulation of Peripheral Sensory Neurons by the Immune System: Implications for Pain Therapy
- Biology, MedicinePharmacological Reviews
- 2011
Future aims include the development of peripherally restricted opioid agonists, selective targeting of opioid-containing immune cells to sites of painful injury, and the augmentation of peripheral ligand and receptor synthesis.
Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions
- Biology, MedicineFront. Pharmacol.
- 2013
The role of opioids in peripheral inflammatory conditions and the clinical implications of targeting peripheral opioid receptors are focused on.
Endogenous opioid and cannabinoid systems modulate the muscle pain: a pharmacological study into the peripheral site.
- BiologyEuropean journal of pharmacology
- 2021
Dual Peripheral Actions of Immune Cells in Neuropathic Pain
- Biology, MedicineArchivum Immunologiae et Therapiae Experimentalis
- 2010
This review analyzes both detrimental and advantageous actions of leukocytes at peripheral nerves in neuropathic pain and indicates that targeting opioid-containing immune cells might represent a new disease-modifying approach based on the use of beneficial effects of neuro-inflammation in painful neuropathies.
Targeting inflammation and wound healing by opioids.
- Biology, MedicineTrends in pharmacological sciences
- 2013
Extending pharmacological spectrum of opioids beyond analgesia: Multifunctional aspects in different pathophysiological states
- Biology, MedicineNeuropeptides
- 2011
Cutaneous Opioid Receptors and Stress Responses: Molecular Interactions and Opportunities for Therapeutic Intervention
- Biology, Medicine
- 2016
Findings on the cutaneous opioid system concerning the treatment of skin pain, itching, wound healing, homeostasis, and ageing will be discussed and open opportunities for medical and cosmetic applications will be suggested.
Bidirectional Regulation of Opioid and Chemokine Function
- Biology, MedicineFrontiers in Immunology
- 2020
The opioid family of GPCRs consists of the classical opioid receptors, designated μ-, κ-, and δ-opioid receptors, and the orphanin-FQ receptor, and these proteins are expressed on both neuronal and…
TNF-α, CXCL-1 and IL-1 β as activators of the opioid system involved in peripheral analgesic control in mice.
- BiologyEuropean journal of pharmacology
- 2021
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