Opioid receptor stimulation suppresses the adrenal medulla hypoxic response in sheep by actions on Ca(2+) and K(+) channels.

Abstract

Before the preganglionic regulation of the adrenal medulla is established, hypoxia acts directly on the chromaffin cells to evoke the secretion of catecholamines. This direct action of hypoxia is suppressed by the gradual development of the preganglionic innervation and we have proposed that opioid peptides released from the adrenal splanchnic nerves may be… (More)

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@article{Keating2004OpioidRS, title={Opioid receptor stimulation suppresses the adrenal medulla hypoxic response in sheep by actions on Ca(2+) and K(+) channels.}, author={Damien J Keating and G Y Rychkov and Michael B. Adams and Hans Holgert and I Caroline Mcmillen and Michael L. Roberts}, journal={The Journal of physiology}, year={2004}, volume={555 Pt 2}, pages={489-502} }