Opioid receptor-mediated inhibition of 3H-dopamine and 14C-acetylcholine release from rat nucleus accumbens slices

Abstract

The release of 14C-ACh from rat nucleus accumbens slices, induced by 15 mM [K+], was inhibited by the µ- and δ-opioid agonists DAMGO and DPDPE, respectively, whereas only the κ agonist U50,488 reduced the release of 3H-DA. The opioid receptors involved appear to be localized on nerve terminals, since blockade of action potential propagation by 1 μM TTX did… (More)
DOI: 10.1007/BF00164575

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@article{Heijna1992OpioidRI, title={Opioid receptor-mediated inhibition of 3H-dopamine and 14C-acetylcholine release from rat nucleus accumbens slices}, author={Menno H. Heijna and François Hogenboom and Arie H. Mulder and Anton N M Schoffelmeer}, journal={Naunyn-Schmiedeberg's Archives of Pharmacology}, year={1992}, volume={345}, pages={627-632} }