Opioid receptor involvement in food deprivation-induced feeding: evaluation of selective antagonist and antisense oligodeoxynucleotide probe effects in mice and rats.

@article{Hadjimarkou2004OpioidRI,
  title={Opioid receptor involvement in food deprivation-induced feeding: evaluation of selective antagonist and antisense oligodeoxynucleotide probe effects in mice and rats.},
  author={Maria M Hadjimarkou and Amritha Singh and Yakov Kandov and Yuriy Israel and Y X Pan and Grace C. Rossi and Gavril W Pasternak and Richard J Bodnar},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2004},
  volume={311 3},
  pages={1188-202}
}
Central administration of general and selective opioid receptor subtype antagonists in the rat has revealed a substantial role for mu, a moderate role for kappa, and a minimal role for delta receptors in the mediation of deprivation-induced feeding. Antisense probes directed against the kappa opioid receptor (KOP), nociceptin opioid receptor (NOP), and delta opioid receptor (DOP) genes in rats result in reductions similar to kappa and delta antagonists, whereas antisense probes directed against… CONTINUE READING