Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations

@article{Eisenstein1998OpioidMO,
  title={Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations},
  author={Toby K. Eisenstein and M E Hilburger},
  journal={Journal of Neuroimmunology},
  year={1998},
  volume={83},
  pages={36-44}
}
The literature describing effects of morphine on cells of the immune system points to the clear conclusion that morphine given in vivo suppresses a variety of immune responses that involve the major cell types in the immune system, including natural killer (NK) cells, T cells, B cells, macrophages and polymorphonuclear leukocytes (PMNs). Depression of NK cell activity has been reported in humans, monkeys and rodents. Similarly, responses of T cells are depressed by morphine, as assessed by… CONTINUE READING

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