Opioid-induced bowel dysfunction: prevalence, pathophysiology and burden

  title={Opioid-induced bowel dysfunction: prevalence, pathophysiology and burden},
  author={Sunil J. Panchal and P M{\"u}ller-Schwefe and John I Wurzelmann},
  journal={International Journal of Clinical Practice},
  pages={1181 - 1187}
As a result of the undesired action of opioids on the gastrointestinal (GI) tract, patients receiving opioid medication for chronic pain often experience opioid-induced bowel dysfunction (OBD), the most common and debilitating symptom of which is constipation. Based on clinical experience and a comprehensive MEDLINE literature review, this paper provides the primary care physician with an overview of the prevalence, pathophysiology and burden of OBD. Patients with OBD suffer from a wide range… CONTINUE READING
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