Opioid effects on intake of sweet solutions depend both on prior drug experience and on prior ingestive experience.

@article{Lynch1990OpioidEO,
  title={Opioid effects on intake of sweet solutions depend both on prior drug experience and on prior ingestive experience.},
  author={W. C. Lynch and Glenn Burns},
  journal={Appetite},
  year={1990},
  volume={15 1},
  pages={23-32}
}
Two experiments investigated the effect of opioids on ingestion of sweet solutions in non-deprived rats. Experiment 1 replicated previous work from our laboratory showing virtually complete inhibition of sucrose and saccharin intake during 10 days of daily naloxone treatment. During recovery, prior naloxone experience significantly stimulated sucrose intake but had no effect on saccharin intake. In the absence of naloxone treatment, ingestive experience alone reduced naloxone's typical intake… CONTINUE READING