Opioid detoxification and naltrexone induction strategies: recommendations for clinical practice.

@article{Sigmon2012OpioidDA,
  title={Opioid detoxification and naltrexone induction strategies: recommendations for clinical practice.},
  author={Stacey C. Sigmon and Adam Bisaga and Edward V Nunes and Patrick G O'connor and Thomas R. Kosten and George E. Woody},
  journal={The American journal of drug and alcohol abuse},
  year={2012},
  volume={38 3},
  pages={
          187-99
        }
}
BACKGROUND Opioid dependence is a significant public health problem associated with high risk for relapse if treatment is not ongoing. While maintenance on opioid agonists (i.e., methadone, buprenorphine) often produces favorable outcomes, detoxification followed by treatment with the μ-opioid receptor antagonist naltrexone may offer a potentially useful alternative to agonist maintenance for some patients. METHOD Treatment approaches for making this transition are described here based on a… CONTINUE READING

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A placebo-controlled trial of memantine as an adjunct to injectable extended-release naltrexone for opioid dependence.

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  • 2014
VIEW 3 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 93 REFERENCES

The Clinical Opiate Withdrawal Scale (COWS).

  • Journal of psychoactive drugs
  • 2003
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

A 33-year follow-up of narcotics addicts.

VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Alpha2 adrenergic agonists for the management of opioid withdrawal.

  • The Cochrane database of systematic reviews
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

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