Opioid binding to rat and guinea-pig neural membranes in the presence of physiological cations at 37 degrees C.

We have identified mu, delta and kappa opioid binding sites in four types of neural membranes under conditions which include physiological concentrations of ions and an incubation temperature of 37 degrees C. We hypothesize that binding parameters determined under these conditions should be more directly comparable with physiological experiments than… (More)