Opioid antagonists in broadly defined behavioral addictions: a narrative review

  title={Opioid antagonists in broadly defined behavioral addictions: a narrative review},
  author={Marcelo Piquet-Pess{\^o}a and L. Fontenelle},
  journal={Expert Opinion on Pharmacotherapy},
  pages={835 - 844}
  • Marcelo Piquet-Pessôa, L. Fontenelle
  • Published 2016
  • Medicine
  • Expert Opinion on Pharmacotherapy
  • ABSTRACT Introduction: Naltrexone (NTX), a mu-opioid receptor antagonist, has been approved for the treatment of alcoholism and opioid dependence. More recently, however, NTX and a related drug, nalmefene (NMF), have also shown positive results for the treatment of gambling disorders. Areas Covered: In this study, we reviewed the trials testing the effect of opioid antagonists (OA) in gambling disorders and in other broadly defined behavioral addictions, including selected DSM-5 disruptive… CONTINUE READING
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