Opioid and non-opioid stress analgesia from cold water swim: importance of stress severity.

@article{Terman1986OpioidAN,
  title={Opioid and non-opioid stress analgesia from cold water swim: importance of stress severity.},
  author={Gregory W. Terman and Mayne J Morgan and Julia Liebeskind},
  journal={Brain research},
  year={1986},
  volume={372 1},
  pages={167-71}
}
We have previously reported that stress severity plays an important role in determining the neurochemical basis of stress-induced analgesia from inescapable footshock. Increasing severity (duration or intensity of continuous footshock) causes a shift in mediation of the resultant analgesia from opioid to non-opioid. In this study, we find that stress severity plays a similar role in analgesia from cold water swim. More severe swims (longer duration or lower water temperature) produce stress… CONTINUE READING

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