Opioid and anti-opioid peptides.

@article{Cesselin1995OpioidAA,
  title={Opioid and anti-opioid peptides.},
  author={François Cesselin},
  journal={Fundamental & clinical pharmacology},
  year={1995},
  volume={9 5},
  pages={
          409-33
        }
}
The numerous endogenous opioid peptides (beta-endorphin, enkephalins, dynorphins ... ) and the exogenous opioids (such as morphine) exert their effects through the activation of receptors belonging to four main types, mu, delta, kappa and epsilon. Opioidergic neurones and opioid receptors are largely distributed centrally and peripherally. It is thus not surprising that opioids have numerous pharmacological effects and that endogenous opioids are thought to be involved in the physiological… CONTINUE READING
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