Opioid Receptor Types Selectively Cointernalize with G Protein-Coupled Receptor Kinases


Activation of G protein-coupled receptors (GPCRs) may bring about their disappearance from the cell membrane, and it is commonly accepted that G protein-coupled receptor kinases (GRKs) play a key function in this mechanism. Opioid receptors belong to the family of GPCRs and are substrates of GRKs. We examined the fate of and -opioid receptors and GRK2 and 3… (More)


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