Opioid Prescriptions for Chronic Pain and Overdose

@article{Dunn2010OpioidPF,
  title={Opioid Prescriptions for Chronic Pain and Overdose},
  author={Kate M. Dunn and Kathleen Saunders and Carolyn M. Rutter and Caleb J. Banta-Green and Joseph O. Merrill and Mark D. Sullivan and Constance Weisner and Michael J. Silverberg and Cynthia I. Campbell and Bruce M. Psaty and Michael Von Korff},
  journal={Annals of Internal Medicine},
  year={2010},
  volume={152},
  pages={85 - 92}
}
BACKGROUND Long-term opioid therapy for chronic noncancer pain is becoming increasingly common in community practice. Concomitant with this change in practice, rates of fatal opioid overdose have increased. The extent to which overdose risks are elevated among patients receiving medically prescribed long-term opioid therapy is unknown. OBJECTIVE To estimate rates of opioid overdose and their association with an average prescribed daily opioid dose among patients receiving medically prescribed… 

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A combined intervention of education and a practice policy that limits opioid doses for patients prescribed chronic opioid therapy may be an important component of system-level strategies to reduce opioid misuse and overdose; it may also help identify patients suitable for medication-assisted treatment for opioid use disorder.

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Established SOAPP-R and DSM thresholds provide an opportunity to identify participants at elevated risk for having experienced an opioid overdose, and data support development of additional concentrated efforts to prevent overdose among chronic pain patients.

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This study sought to characterize opioid use after an overdose among patients receiving long-term opioid therapy for noncancer pain among patients from a large U.S. health insurer with members in all 50 states.

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Opioid therapy for chronic pain in the United States: Promises and perils

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