Opioid-Induced Hyperalgesia in the Nonsurgical Setting: A Systematic Review

@article{Yang2019OpioidInducedHI,
  title={Opioid-Induced Hyperalgesia in the Nonsurgical Setting: A Systematic Review},
  author={D. Yang and B. Sin and Joshua Beckhusen and D. Xia and R. Khaimova and I. Iliev},
  journal={American Journal of Therapeutics},
  year={2019},
  volume={26},
  pages={e397–e405}
}
Background: Opioid-induced hyperalgesia (OIH) is a phenomenon that causes an increased pain sensitization and perception of pain to noxious stimuli secondary to opioid exposure. [...] Key Method This review included randomized controlled trials with objectives to identify OIH in the nonsurgical setting. The clinical outcomes of interest were identification of OIH, adverse events, and impact of OIH on opioid consumption. Results: The search identified 8 studies that fulfilled the criteria.Expand
Treatment of Neuropathic Pain
Undiscovered morphine. The effects of the long-term use of the opioids
Implementation of an Advanced Pharmacy Practice Model in the Emergency Department
Opioid Crises-the Perspective From a Developing Country.

References

SHOWING 1-10 OF 30 REFERENCES
The endogenous opioid system is not involved in modulation of opioid-induced hyperalgesia.
Opioid therapy for chronic nonmalignant pain: a review of the critical issues.
  • R. Portenoy
  • Medicine
  • Journal of pain and symptom management
  • 1996
Hyperalgesia in heroin dependent patients and the effects of opioid substitution therapy.
Target-controlled dosing of remifentanil during cardiac surgery reduces postoperative hyperalgesia.
...
1
2
3
...