Opiate-dependent modulation of adenylate cyclase.


Reactions mediated by the opiate receptors that inhibit adenylate cyclase (EC are closely coupled to subsequent reactions that gradually increase adenylate cyclase activity of neuroblastoma X glioma NG108-15 hybrid cells. Opiate-treated cells have higher basal-, prostaglandin E1-, and 2-chloroadenosine-stimulated activities than do control cells… (More)


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