Ophthalmic timolol in a hydrogel vehicle leads to minor inter-individual variation in timolol concentration in aqueous humor.

Abstract

Ophthalmic timolol has been used for decades in the treatment of glaucoma and ocular hypertension, traditionally in aqueous 0.5% eye drops. Recently a timolol 0.1% hydrogel has been developed to improve systemic safety. The aim of the present study was to compare aqueous humor timolol concentrations after administration of 0.1% hydrogel and aqueous 0.5… (More)
DOI: 10.1016/j.ejps.2008.10.004

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@article{Volotinen2009OphthalmicTI, title={Ophthalmic timolol in a hydrogel vehicle leads to minor inter-individual variation in timolol concentration in aqueous humor.}, author={Marjo Volotinen and Jukka M{\"a}enp{\"a}{\"a} and Hannu Kautiainen and Ari Tolonen and Jouko Uusitalo and Auli Ropo and Heikki Vapaatalo and Esko Aine}, journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences}, year={2009}, volume={36 2-3}, pages={292-6} }