Ophiopogonin B induces apoptosis, mitotic catastrophe and autophagy in A549 cells.


Ophiopogonin B (OP-B), a saponin compound isolated from Radix Ophiopogon japonicus, was verified to inhibit cell proliferation in numerous non-small cell lung cancer (NSCLC) cells in our previous study. However, the precise mechanisms of action have remained unclear. In the present study, we mainly investigated the effects of OP-B on adenocarcinoma A549… (More)
DOI: 10.3892/ijo.2016.3514


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