Ophidian envenomation strategies and the role of purines.

  title={Ophidian envenomation strategies and the role of purines.},
  author={Steven D Aird},
  journal={Toxicon : official journal of the International Society on Toxinology},
  volume={40 4},
  • Steven D Aird
  • Published 2002 in
    Toxicon : official journal of the International…
Snake envenomation employs three well integrated strategies: prey immobilization via hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine, guanosine and inosine) evidently play a central role in the envenomation strategies of most advanced snakes. Purines constitute the perfect multifunctional toxins, participating simultaneously in all three envenomation strategies. Because they are endogenous regulatory compounds in all vertebrates, it is impossible for any… CONTINUE READING


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