Operculina turpethum (Linn.) Silva Manso as a Medicinal Plant Species: A Review on Bioactive Components and Pharmacological Properties

@article{Gupta2017OperculinaT,
  title={Operculina turpethum (Linn.) Silva Manso as a Medicinal Plant Species: A Review on Bioactive Components and Pharmacological Properties},
  author={Shweta Gupta and Akash Ved},
  journal={Pharmacognosy Reviews},
  year={2017},
  volume={11},
  pages={158 - 166}
}
Operculina turpethum (Linn.) (OT) Silva Manso belongs to the family Convolvulaceae. This review incorporates literature for the phytochemical and pharmacological profile of OT herb. Exhaustive literature survey was done using all the details on phytochemistry and pharmacology of OT available. This herb was found to be a potent source of bioactive compounds such as α- and β-turpethein, turpethinic acids (A, B, C, D, and E), coumarins, cycloartenol, lanosta-5-ene, 24-methylene-δ-5-lanosterol… 
PHYTOCHEMISTRY AND PHARMACOLOGICAL POTENTIAL OF OPERCULINA TURPETHUM
TLDR
The current review article is an effort to provide comprehensive information on chemical and pharmacological profile of the Operculina turpethum.
Antidiabetic, antioxidant and anti-inflammatory activity of medicinal plants collected from nearby area of Junagadh, Gujarat
TLDR
Phytochemical analysis revealed the presence of glycosides, flavonoids, alkaloids, tannins and steroids in different extracts of medicinal plants which might be responsible for significant in vitro antidiabetic, antioxidant and antiinflammatory activities.
Ameliorative potential of Operculina turpethum against streptozotocin-induced diabetes in rats: biochemical and histopathological studies
TLDR
The in-vivo antidiabetic study was carried out on Sprague-Dawley rats using high-fat diet (HFD) feeding streptozotocin (STZ) diabetic model, and the biochemical, histopathology research findings represent that the OTFF fraction acts as a potential therapeutic agent for Type II diabetes mellitus.
Operculina turpethum (L.) Silva Manso (Convolvulaceae)
TLDR
Ethanol root extract restored RBC and WBC counts, and Hb content due to NDMA hematological toxicity in mice, and protected against APAP-, and NDMA-hepatotoxicity in rats and dogs, and also exhibited moderate antioxidant and radical scavenging activities.
A comprehensive review on Turbud (Operculina turpethum (L): A potential unani drug
Turbud (Operculina turpethum (L.) Silva Manso) belongs to family Convolvulaceae, is a Potent and well-known medicinal herb, used in Unani system of medicine to treat various ailments. The word Turbud
Development of a Validated HPTLC Method for Quantification of Scopoletin in Ipomoea turpethum Root and its Market Formulations
TLDR
A simple method of identification and quantification of scopoletin in I. turpethum and it was concluded that in F-5 being vati, presence of excipients and method of preparation might have influenced the scopeletin content.
Relevance of Ethnopharmacological Research Related to Threatened Medicinal Plants Associated with Traditional Knowledge
Bio-prospecting of plants based on traditional knowledge is an important area of research to develop novel process/products in terms of herbal/Ayurvedic drugs, nutraceuticals, functional foods, and
Underutilized green leafy vegetables: frontier in fortified food development and nutrition.
From the ancient period, Green leafy vegetables (GLV) are part of the daily diet and were believed to have several health beneficial properties. Later it has been proved that GLV has outstanding
Hepatoprotective action of Nagdantyadi ghrita: A literature review
TLDR
Foods of NG are proven to possess hepatoprotective action in context of Ayurveda literature and this study supports the pharmacological potential of NG and its ingredients with scientific results.
Conservation and Utilization of Threatened Medicinal Plants
TLDR
This chapter makes an attempt to compile drug discoveries from some threatened medicinal plant species so as to give a scientific account of their future use, as well as their ability to be a source of new miracle drugs that can fight against chronic diseases.
...
...

References

SHOWING 1-10 OF 87 REFERENCES
Ameliorative Effects of Operculina turpethum and its Isolated Stigma-5,22dien-3-o-β-D-glucopyranoside on the Hematological Parameters of Male Mice Exposed to N-Nitrosodimethylamine, a Potent Carcinogen
TLDR
The results show that the extract of Operculina turpethum is relatively safe following oral administration and have possible stimulatory effect on red blood cell production and there was dose dependent therapeutic effect.
Antiproliferative constituents from umbelliferae plants. V. A new furanocoumarin and falcarindiol furanocoumarin ethers from the root of Angelica japonica.
The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth. From this extract, a new furanocoumarin named japoangelone
COMPARATIVE ASSESSMENT OF COUMARIN CONTENT IN ROOT BARKS AND SEEDS OF OPERCULINA TURPETHUM, A VULNERABLE MEDICINAL PLANT OF ODISHA, INDIA
TLDR
Present study encourages propagation and cultivation of O. turpethum with the wild stock plants from Khurda region of Odisha having comparatively higher coumarin content especially in the root-barks.
Pharmacognostic Studies on Leaf of Operculina turpethum (L.) Silva Manso
TLDR
The study opened a window to the bioprospecting of leaf of O. turpethum for various medicinal principles as well as properties.
Antibacterial and Cytotoxic Activities of Extracts and Isolated Compounds of Ipomoea turpethum
TLDR
Three compounds H-1, H-2 & CH-2 isolated from the chloroform extract of stem of Ipomoea turpethum and the crude petroleum ether, chloro form and ethyl acetate extracts were screened against thirteen pathogenic bacteria for their antibacterial activities.
Assessment of Bioactivity of Indian Medicinal Plants Using Brine Shrimp (Artemia salina) Lethality Assay
TLDR
The present study supports that brine shrimp bioassay is simple reliable and convenient method for assessment of bioactivity of medicinal plants and lends support for their use in traditional medi- cine.
Comparative analysis of the Phytochemicals present in differentextracts of Operculina turpethum
Plant kingdom harbours an inexhaustible source of active ingredients valuable in the management of many intractable diseases. Phytochemical techniques played a significant role in searching raw
Bioactive dammarane-type saponins from Operculina turpethum.
TLDR
Four new dammarane-type saponins, operculinosides A-D (1-4), were isolated from the aerial parts of Operculina turpethum and showed significant protective activities against d-galactosamine-induced toxicity in L-02 human hepatic cells.
Micropropagation and Antimicrobial Activity of 'Operculina turpethum' (Syn. 'Ipomoea turpethum'), an Endangered Medicinal Plant
TLDR
In terms of antibacterial properties petroleum ether and ethanol extracts of leaves showed potential antimicrobial properties against several human pathogenic bacteria with a minimum inhibitory concentration (MIC) ranged from 0.13-0.75 mg ml -1.
ALTERATIONS INDUCED BY N-NITROSODIMETHYLAMINE AND ETHANOLIC ROOT EXTRACT OF OPERCULINA TURPETHUM IN SERUM LIPID PROFILE OF MALE ALBINO MICE
The present study investigated the protective effect of ethanolic root extract of Operculina turpethum on serum lipid profile in male albino mice intoxicated with N-Nitrosodimethylamine (NDMA).
...
...