Operative venodilation: a previously unsuspected factor in the cause of postoperative deep vein thrombosis.

@article{Comerota1989OperativeVA,
  title={Operative venodilation: a previously unsuspected factor in the cause of postoperative deep vein thrombosis.},
  author={Anthony James Comerota and Graeme John Stewart and P D Alburger and K A Smalley and John Valery White},
  journal={Surgery},
  year={1989},
  volume={106 2},
  pages={301-8: discussion 308-9}
}
Intraoperative venodilation in veins distant from the site of operation has been shown to occur in animals and has been directly correlated with focal venous endothelial damage. This exposure of subendothelial collagen could serve as initiation sites for thrombus formation. This study tests the hypothesis that human beings (1) significant operative venodilation occurs and that it correlates with postoperative deep venous thrombosis (DVT); (2) operative venodilation can be pharmacologically… CONTINUE READING

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