Operative monitoring of parathyroid gland hyperfunction.

  title={Operative monitoring of parathyroid gland hyperfunction.},
  author={George L. Irvin and Victor Dembrow and D L Prudhomme},
  journal={American journal of surgery},
  volume={162 4},
With a 20-year experience of more than 700 parathyroidectomies, our persistent hypercalcemic postoperative failure rate of 7% has remained constant. Reasons for failure have been misdiagnosis or inability of the surgeon to detect and excise all hypersecreting glands. We have modified a commercially available immunoradiometric assay for intact parathyroid hormone (PTH) resulting in a 15-minute turnaround time. Since intact PTH has a half-life measured in minutes, whole blood samples taken 10… CONTINUE READING