Operative Time and Other Outcomes of the Electrothermal Bipolar Vessel Sealing System (LigaSure™) Versus Other Methods for Surgical Hemostasis: A Meta-Analysis

  title={Operative Time and Other Outcomes of the Electrothermal Bipolar Vessel Sealing System (LigaSure{\texttrademark}) Versus Other Methods for Surgical Hemostasis: A Meta-Analysis},
  author={Alex Macario and Franklin Dexter and Jennifer Sypal and Ned Cosgriff and B. Todd Heniford},
  journal={Surgical Innovation},
  pages={284 - 291}
A meta-analysis was performed of 29 prospective, randomized trials (published January 1, 2000, to August 14, 2007) comparing an electrothermal bipolar vessel sealing system (EBVS-LigaSure™, Covidien) (total n = 1107 patients) with either clamping with suture ligation/ electrocauterization (n = 1079 patients) or ultrasonic energy (eg, Harmonic Scalpel®, Johnson & Johnson). Hemorrhoidectomy (12 articles), hysterectomy (4 articles), and thyroidectomy (3 articles) were the most common procedures… 
ENERgized vessel sealing systems versus CONventional hemostasis techniques in thyroid surgery—the ENERCON systematic review and network meta-analysis
This meta-analysis shows superiority of ultrasonic devices in terms of operation time compared with conventional hemostasis techniques in thyroid surgery, with no detriment to safety outcomes.
Effectiveness of electrothermal bipolar vessel-sealing devices versus other electrothermal and ultrasonic devices for abdominal surgical hemostasis: a systematic review
Vessel-sealing devices may be considered safe and their use may reduce costs due to reduced blood loss and shorter operating time in some abdominal surgical procedures compared to mono- or bipolar electrothermal devices.
Bipolar Electrothermal Vessel Sealing System and 5-mm 2 Expandable Trocar Approach in Pediatric Laparoscopic Varicocelectomy: A Successful Time-effective Technical Refinement
Laroscopic Palomo varicocele surgery for pediatric patients using Ligasure as spermatic vessels sealant and only 2 radially expandable 5-mm trocars is a safe, feasible, and time-effective technical improvement.
Experimental comparison of mesenteric vessel sealing and thermal damage between one bipolar and two ultrasonic shears devices (Br J Surg 2011; 98: 797–800)
All three instruments were equally good at sealing blood vessels, with bursting pressures well above physiological blood pressure levels.
Electrothermal bipolar vessel sealing system (LigaSure™) for hemostasis during thyroid surgery: a comprehensive review
A focus is given to LigaSure™ (Covidien, Dublin, Ireland) technology because it has been studied most thoroughly in the literature and will also evaluate studies comparing the EBVS with Harmonic Scalpel technology for thyroid surgery.
Comparison of the Electrosurgical Bipolar Vessel Sealing with the Standard Suture Technique in Patients with Diverse Benign Indications for Abdominal Hysterectomy: A Controlled Trial
L LigaSure is an effective and reliable device that provides a significant reduction in quantity of bleeding, reduction in operation time and postoperative VAS scores.
Harmonic versus LigaSure hemostasis technique in thyroid surgery: A meta-analysis.
The present meta-analysis indicated superiority of Harmonic Scalpel only in terms of surgical time compared with LigaSure hemostasis techniques in open thyroid surgery.
Efficacy of Electrosurgical Bipolar Vessel Sealing for Abdominal Hysterectomy with Uterine Myomas More than 14 Weeks in Size: A Randomized Controlled Trial
In myoma uteri cases larger than 14 weeks in size, LigaSure vessel sealing is a secure and comfortable method for surgeons to achieve shorter operation times in abdominal hysterectomy.


Hepatic resections by means of electrothermal bipolar vessel device (EBVS) LigaSure V: early experience
EBVS proved to be safe and effective for liver resection by means of this device, statistically significant benefits concerning blood loss, total bile salts, and hemoglobin postoperative leakage were found.
Comparative study of electrothermal bipolar vessel sealer and ultrasonic coagulating shears in laparoscopic colectomy
The use of the EBVS will enable surgeons to reduce the total operating time for laparoscopic colectomy and the required time for mesocolon dissection was significantly shorter when the EB VS was used in both laparosc transverse coLECTomy and sigmoidectomy.
A comparison of laparoscopic bipolar vessel sealing devices in the hemostasis of small-, medium-, and large-sized arteries.
The LS produces supraphysiologic seals with significantly higher bursting pressures than the PK in vessels ranging from 4 to 7 mm, and although thermal spread increases with vessel size, the degree of lateral thermal injury is no different between the two instruments.
Use of the electrothermal bipolar vessel system (EBVS) in laparoscopic adrenalectomy: a prospective study
EBVS in LA may provide a significantly short operating time and blood loss and the main surgical parameters collected concerned operative time, major and minor complications, conversion rate, blood loss, hospital stay and histology.
Comparison of ultrasonic energy, bipolar thermal energy, and vascular clips for the hemostasis of small-, medium-, and large-sized arteries
The EBVS can be used confidently in vessels up to 7 mm, and the spread of thermal injury from the UCS and the EBVS was compared, with no difference in the thermal spread of the LigaSure vessel sealer and the UCS.
Effectiveness of the ultrasonic coagulating shears, LigaSure vessel sealer, and surgical clip application in biliary surgery: a comparative analysis.
The ultrasonic coagulating shears and electrothermal bipolar vessel sealer failed to maintain seal integrity in the in vivo animal study and should not be used for transection of the cystic duct or major hepatic ducts during hepatobiliary surgery.
Vascular pedicle ligation techniques during laparoscopic colectomy. A prospective randomized trial.
The LigaSure Atlas is more cost effective during laparoscopic colectomy, especially total colectome, and may allow the surgeon more versatility in its application.
Energy Sources for Laparoscopic Colectomy: A Prospective Randomized Comparison of Conventional Electrosurgery, Bipolar Computer-Controlled Electrosurgery and Ultrasonic Dissection. Operative Outcome and Costs Analysis
Surgical time was significantly longer in patients operated on with conventional electrosurgery vs the Harmonic Scalpel or computed-based bipolar energy devices, and this finding correlated with a significant reduction in intraoperative blood loss.
Ligasure versus sutures in bladder replacement with Montie ileal neobladder after radical cystectomy.
  • P. Manasia, A. Alcaraz, J. Alcover
  • Medicine
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • 2003
Ligasure is a safe and effective alternative to sutures in cystectomy and bladder replacement, resulting in decreased blood loss and significant time saving.