Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project.

@article{Pulley2012OperationalIO,
  title={Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project.},
  author={Jill M. Pulley and Joshua C. Denny and Josh F. Peterson and Gordon R. Bernard and Cindy L. Vnencak-Jones and Andrea H. Ramirez and Jessica T. Delaney and Erica A. Bowton and Kyle Brothers and Katherine Johnson and Dana C. Crawford and Jonathan S. Schildcrout and Daniel R. Masys and Holli H. Dilks and Russell A. Wilke and Ellen Wright Clayton and Elizabeth K B Shultz and Michael Laposata and Jacob G. McPherson and Jim Jirjis and Dan M. Roden},
  journal={Clinical pharmacology and therapeutics},
  year={2012},
  volume={92 1},
  pages={
          87-95
        }
}
The promise of "personalized medicine" guided by an understanding of each individual's genome has been fostered by increasingly powerful and economical methods to acquire clinically relevant information. We describe the operational implementation of prospective genotyping linked to an advanced clinical decision-support system to guide individualized health care in a large academic health center. This approach to personalized medicine entails engagement between patient and health-care provider… CONTINUE READING
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