Operational criteria for selecting a cDNA microarray data normalization algorithm.

@article{Argyropoulos2006OperationalCF,
  title={Operational criteria for selecting a cDNA microarray data normalization algorithm.},
  author={Christos Argyropoulos and Aristotelis A. Chatziioannou and George Nikiforidis and Aris L. Moustakas and George Kollias and Vassilis Aidinis},
  journal={Oncology reports},
  year={2006},
  volume={15 Spec no.},
  pages={
          983-96
        }
}
Microarray technology allows gene expression profiling at a global level. Many algorithms for the normalization of raw microarray data have been proposed, but no attempt has yet been made to propose operationally verifiable criteria for their comparative evaluation, which is necessary for the selection of the most appropriate method for a given dataset. This study develops a set of operational criteria for assessing the impact of various normalization algorithms in terms of accuracy (bias… CONTINUE READING

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