Operation Everest II: oxygen transport during exercise at extreme simulated altitude.

@article{Sutton1988OperationEI,
  title={Operation Everest II: oxygen transport during exercise at extreme simulated altitude.},
  author={John R. Sutton and John R T Reeves and Peter D. Wagner and B. M. Groves and Allen Cymerman and Mark K. Malconian and Paul B. Rock and Patricia M. Young and Stephen D. Walter and Charles S. Houston},
  journal={Journal of applied physiology},
  year={1988},
  volume={64 4},
  pages={1309-21}
}
A decrease in maximal O2 uptake has been demonstrated with increasing altitude. However, direct measurements of individual links in the O2 transport chain at extreme altitude have not been obtained previously. In this study we examined eight healthy males, aged 21-31 yr, at rest and during steady-state exercise at sea level and the following inspired O2 pressures (PIO2): 80, 63, 49, and 43 Torr, during a 40-day simulated ascent of Mt. Everest. The subjects exercised on a cycle ergometer, and… CONTINUE READING
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