Operant Conditioning of Cortical Unit Activity

  title={Operant Conditioning of Cortical Unit Activity},
  author={E. Fetz},
  pages={955 - 958}
  • E. Fetz
  • Published 1969
  • Biology, Medicine
  • Science
The activity of single neurons in precentral cortex of unanesthetized monkeys (Macaca mulatta) was conditioned by reinforcing high rates of neuronal discharge with delivery of a food pellet. Auditory or visual feedback of unit firing rates was usually provided in addition to food reinforcement. After several training sessions, monkeys could increase the activity of newly isolated cells by 50 to 500 percent above rates before reinforcement. 
Conditioning of the pyramidal response in unanesthetized cats
The effect of a classical conditioning paradigm on the evoked pyramidal activity in immobilized cats was examined. The lower-frequency evoked pyramidal discharge appears to be a more robust measureExpand
Reinforcement schedules differentially affect learning in neuronal operant conditioning in rats
Neuronal firing rates were enhanced in the FR but not in the VR schedule during conditioning, suggesting that the principles of operant conditioning of neuronal activity are different from those of behavioral responses. Expand
Habituation of the pyramidal response in unanesthetized cat.
The results are consistent with a dual-process theory of habituation, and an early component of the evoked pyramidal activity exhibited habituation while a later component showed sensitization. Expand
Operant conditioning of cortical steady potential responses in rats.
It is concluded that changes in cortical SP responses can be operantly conditioned. Expand
Operant control of precentral neurons: Bilateral single unit conditioning
The data indicate that although many precentral units may change firing patterns when the monkey attends to the operant task, the reinforced changes in firing pattern are not the result of a generalized phenomenon at the spinal level. Expand
Operant conditioning of tonic neuronal firing rates from single units in monkey motor cortex
This study used an operant paradigm to train Macaca mulatta monkeys for changing phasic firing patterns to tonic patterns in single precentral neurons and demonstrated that the shift in firing pattern was not a response to alerting. Expand
Operant conditioning of firing patterns in monkey cortical neurons
In roughly 79% of these runs, the monkey was able to modulate successfully the firing rate of a cortical neuron between two frequency bands on command and was also able to adjust the rate to several different frequency bands. Expand
Low-Frequency Neuronal Oscillations as Operant Processing of the Mechanisms of Integration, Conditioning, and Plasticity
Neuron activity in the somatosensory cortex of the rabbit can undergo operant conditioning in accordance with a specified algorithm for biofeedback control of nociceptive stimulation to produceExpand
Effects of operantly conditioning epileptic unit activity on seizure frequencies and electrophysiology of neocortical experimental foci.
It is concluded that single cell operant conditioning wasassociated with a decrease in the proportion of single units exhibiting interictal burst activity but not consistently associated with a reduction of seizure frequency. Expand
Operant conditioning of single unit activity in parietal cortex
Two rhesus monkeys were trained to control firing patterns of single neurons in parietal cortex using an operant task previously applied to the study of precentral units, indirectly supporting conclusions that operant control of cortical units is peripherally mediated and does not primarily involve a 'central' or 'open loop' system. Expand


Response of Neurones in the Motor Cortex during Performance of a Simple Repetitive Arm Movement
ANALYSIS of the firing pattern of single cells in the brains of unanaesthetized animals promises to be a useful approach towards understanding brain mechanisms involved in the control of movement.Expand
Deafferentation in Monkeys: Effect on Conditioned Grasp Response
That subjects were able to learn this response with a deafferented hand, in the absence of vision, indicated that purposive movements of the distal musculature are less under the control of peripheral feedback than had been generally believed. Expand
Control and Training of Individual Motor Units
Experiments clearly demonstrate that with the help of auditory and visual cues man can single out motor units and control their isolated contractions. Experiments on the training of this control,Expand
Single unit activity related to behavior motivated by food reward
Abstract In our earlier works we observed an inhibition of single unit activity recorded from the globus pallidus during specific goal oriented sequences of behavior. The present report describes twoExpand
Relation of pyramidal tract activity to force exerted during voluntary movement.
  • E. Evarts
  • Psychology, Medicine
  • Journal of neurophysiology
  • 1968
It was found that for many PTNs, responses to the conditioned stimulus preceded the first peripheral electromyographic correlates of the conditioned response (wrist extension) and showed that they were not consequent upon feedback resulting from the movement. Expand
Tungsten Microelectrode for Recording from Single Units.
  • D. Hubel
  • Materials Science, Medicine
  • Science
  • 1957
Three subjects which were unknown or ignored ten years ago are now prominent: the proprioceptive control of the respiratory muscles; the in­ trinsic properties of these muscles; and the mechanics ofExpand
A similar reduction of globus pallidus unit activity following food reinforcement has been reported
  • Physiol. Behav. Brain Res
  • 1968
A similar reduction of globus pallidus unit activity following food reinforcement has been reported by
  • Physiol. Behav
  • 1968