Opening of Ca2+ channels in isolated red beet root vacuole membrane by inositol 1,4,5-trisphosphate

@article{Alexandra1990OpeningOC,
  title={Opening of Ca2+ channels in isolated red beet root vacuole membrane by inositol 1,4,5-trisphosphate},
  author={J. Alexandra and J. P. Lassalles and Raymond T. Kado},
  journal={Nature},
  year={1990},
  volume={343},
  pages={567-570}
}
INOSITOL 1,4,5-trisphosphate (InsP3) is often implicated in pathways that couple extracellular signals to cellular calcium-dependent effectors. Various experiments have demonstrated that InsP3 can release calcium from intracellular stores in animal cells1–5 by acting on a specific receptor6. There are also reports that InsP3 is important in plant cells7–12. Using patch-clamp techniques13–15, we have now obtained direct measurements of a Ca2+ current in the isolated red beet root vacuole. This… CONTINUE READING
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