Open versus closed management of the abdomen in the surgical treatment of severe secondary peritonitis: a randomized clinical trial.

@article{Robledo2007OpenVC,
  title={Open versus closed management of the abdomen in the surgical treatment of severe secondary peritonitis: a randomized clinical trial.},
  author={Felipe A Robledo and Enrique Luque-de-Le{\'o}n and Roberto M Su{\'a}rez and Patricio S{\'a}nchez and Mauricio de-la-Fuente and Adriana K N Vargas and Juan Felipe Mier},
  journal={Surgical infections},
  year={2007},
  volume={8 1},
  pages={63-72}
}
BACKGROUND Despite recent advances in diagnosis, antimicrobial therapy, and intensive care support, operative treatment remains the foundation of the management of patients with severe secondary peritonitis (SSP). This management is based on three fundamental principles: (1) Elimination of the source of infection; (2) reduction of bacterial contamination of the peritoneal cavity; and (3) prevention of persistent or recurrent intra-abdominal infection. Although recent studies have emphasized the… CONTINUE READING
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