Open-label study of the safety and effectiveness of long-term therapy with extended-release tramadol in the management of chronic nonmalignant pain.

@article{Pascual2007OpenlabelSO,
  title={Open-label study of the safety and effectiveness of long-term therapy with extended-release tramadol in the management of chronic nonmalignant pain.},
  author={Maria Luz G Pascual and Rosa Rosanna B Fleming and Theophilus J. Gana and Gary J Vorsanger},
  journal={Current medical research and opinion},
  year={2007},
  volume={23 10},
  pages={2531-42}
}
BACKGROUND Tramadol ER* is a once-daily oral analgesic for management of moderate-to-moderately severe chronic pain in adults who require around-the-clock treatment of pain. This study evaluated long-term safety of tramadol ER and effectiveness outcomes in the management of chronic, nonmalignant pain. METHODS Patients enrolled directly for approximately 1 year of open-label tramadol ER treatment if they had chronic, nonmalignant pain (n = 919), or 'rolled over' for 38 weeks of open-label… CONTINUE READING
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