Open and continuous fermentation: Products, conditions and bioprocess economy

  title={Open and continuous fermentation: Products, conditions and bioprocess economy},
  author={Teng Li and Xiangbin Chen and Jinchun Chen and Qiong Wu and Guoqiang Chen},
  journal={Biotechnology Journal},
Microbial fermentation is the key to industrial biotechnology. Most fermentation processes are sensitive to microbial contamination and require an energy intensive sterilization process. The majority of microbial fermentations can only be conducted over a short period of time in a batch or fed‐batch culture, further increasing energy consumption and process complexity, and these factors contribute to the high costs of bio‐products. In an effort to make bio‐products more economically competitive… 

Non-sterile fermentations for the economical biochemical conversion of renewable feedstocks

  • Zhu ChenCaixia Wan
  • Biotechnology Letters
  • 2017
Heavy reliance on petroleum-based products drives continuous exploitation of fossil fuels, and results in serious environmental and climate problems. To address such an issue, there is a shift from

Fermentation Economics and Future Prospects

To improve the link between off-site and integrated production, more comprehensive and revised data for off- Site enzyme production are necessary, as also additional upscaling and enactment of both off- site and combined processes.

Comprehensive assessment of the l-lysine production process from fermentation of sugarcane molasses

The main results show how the operating conditions, process design, and selection of evaluation criteria can influence in the conceptual design of the l-lysine production process.

Non-thermal plasma for revalorization of a complex waste substrate in open lactic acid fermentation

Purpose: Stillage is the main by-product of bioethanol production and cost of its treatment significantly affects the economy of bioethanol production. Utilization of stillage for fermentative lactic

Fermentative Production of Lactic Acid as a Sustainable Approach to Valorize Household Bio-Waste

Source-sorted organic portion of municipal solid waste (bio-waste) can be fermented to lactic acid, a platform chemical widely used in the production of biodegradable polymers, green solvents, and

Non-Sterilized Fermentation of 2,3-Butanediol with Seawater by Metabolic Engineered Fast-Growing Vibrio natriegens

The feasibility of non-sterilized fermentation using seawater to replace freshwater and other valuable chemicals may also be produced through metabolic engineering of the emerging synthetic biology chassis V. natriegens is confirmed.

Non-thermal plasma and ultrasound-assisted open lactic acid fermentation of distillery stillage

Around 20% better revalorization of stillage by PT was achieved when compared with conventional sterilization, and an excellent L (+) LA stereoselectivity was attained after PT.



State of the Art in Immobilized/Encapsulated Cell Technology in Fermentation Processes

Immobilized yeast cells are being used in various bio-industries but also could be beneficially implemented in industries based on ethanol fermentation. For reasons including faster fermentation

Continuous Primary Fermentation of Beer with Yeast Immobilized on Spent Grains—The Effect of Operational Conditions

A one-stage continuous primary beer fermentation with immobilized brewing yeast was studied. The objective of the work was to optimize the operational conditions (aeration and temperature) in terms

Continuous Beer Fermentation Using Immobilized Yeast Cell Bioreactor Systems

Recent development in reactor design and understanding of immobilized cell physiology, together with application of novel carrier materials, could provide a new stimulus to both research and application of this promising technology.

Ethanol fermentation technologies from sugar and starch feedstocks.

Biotechnological advantages of laboratory-scale solid-state fermentation with fungi

This review will focus on research work allowing comparison of the specific biological particulars of enzyme, metabolite and/or spore production in SSF and in SmF.

Immobilized yeast cell systems for continuous fermentation applications

This paper focuses on the practical use of continuous fermentation and cell immobilization systems for beer production, and the impact of immobilization on cell physiology and fermentation performance is discussed.

Solid-state fermentation--are there any biotechnological advantages?

Solid-State Fermentation Systems—An Overview

  • C. Krishna
  • Chemistry, Medicine
    Critical reviews in biotechnology
  • 2005
The relevance of applying SSF technology in the production of mycotoxins, biofuels, and biocontrol agents is discussed, and the need for adopting SSFtechnology in bioremediation of toxic compounds, biological detoxication of agro-industrial residues, andBiotransformation of agri-products and residues is emphasized.