Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy.

@article{Morali2006OpenNC,
  title={Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy.},
  author={Giancarlo Morali and Franco Polatti and Elena N Metelitsa and Paolo Mascarucci and Paola Magnani and Giovanni Brunenghi Marr{\`e}},
  journal={Arzneimittel-Forschung},
  year={2006},
  volume={56 3},
  pages={
          230-8
        }
}
Menopause is often associated with vaginal atrophy and related symptoms, such as vaginal dryness, burning, itching, and dyspareunia, decrease in libido and in general a decrease in the quality of life. The common treatment up to the 1990's has been the oral hormone replacement therapy (HRT), but this treatment has been consequently re-considered due to its adverse effects. Topical estrogenic products have been subsequently developed to minimize the systemic adverse effects of the oral HRT, but… Expand
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