Opacity proteins increase Neisseria gonorrhoeae fitness in the female genital tract due to a factor under ovarian control.

@article{Cole2010OpacityPI,
  title={Opacity proteins increase Neisseria gonorrhoeae fitness in the female genital tract due to a factor under ovarian control.},
  author={Jessica G. Cole and Nanette B Fulcher and Ann E Jerse},
  journal={Infection and immunity},
  year={2010},
  volume={78 4},
  pages={1629-41}
}
The neisserial opacity (Opa) proteins are a family of antigenically distinct outer membrane proteins that undergo phase-variable expression. Opa(+) variants of Neisseria gonorrhoeae strain FA1090 are selected in a cyclical pattern from the lower genital tract of estradiol-treated mice. Here we show that cyclical recovery of Opa(+) gonococci does not occur… CONTINUE READING