Oocyte signals derived from polyunsaturated fatty acids control sperm recruitment in vivo

@article{Kubagawa2006OocyteSD,
  title={Oocyte signals derived from polyunsaturated fatty acids control sperm recruitment in vivo},
  author={Homare M. Kubagawa and Jennifer L Watts and Chad Corrigan and Johnathan W. Edmonds and Elizabeth S. Sztul and John Browse and Michael A Miller},
  journal={Nature Cell Biology},
  year={2006},
  volume={8},
  pages={1143-1148}
}
A fundamental question in animal development is how motile cells find their correct target destinations. During mating in the nematode Caenorhabditis elegans, males inject sperm through the hermaphrodite vulva into the uterus. Amoeboid sperm crawl around fertilized eggs to the spermatheca – a convoluted tube where fertilization occurs. Here, we show that polyunsaturated fatty acids (PUFAs), the precursors of eicosanoid signalling molecules, function in oocytes to control directional sperm… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 71 CITATIONS, ESTIMATED 60% COVERAGE

119 Citations

01020'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 119 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 22 REFERENCES

elegans sperm bud vesicles to deliver a meiotic maturation signal to distant oocytes

  • J. McCarter, B. Bartlett, T. Dang, T. Schedl
  • Development
  • 2005

lipid mediators grease the way

  • A. D. Luster, Tager, A. M. T-cell trafficking in asthma
  • Nat Rev Immunol 4, 711-24
  • 2004

Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans

  • B. Grant, D. Hirsh
  • Proc Natl Acad Sci U S A
  • 2002

Similar Papers

Loading similar papers…