Oocyte development in bovine primordial follicles is promoted by activin and FSH within a two-step serum-free culture system.

@article{McLaughlin2010OocyteDI,
  title={Oocyte development in bovine primordial follicles is promoted by activin and FSH within a two-step serum-free culture system.},
  author={Marie McLaughlin and Evelyn E Telfer},
  journal={Reproduction},
  year={2010},
  volume={139 6},
  pages={971-8}
}
Quiescent follicles of large mammals initiate growth within cultured pieces of ovarian cortex. Systems capable of sustaining in vitro development from this early stage until oocyte maturation would allow investigation of mechanisms regulating oocyte development in its entirety. The aims of this study were 1) to determine whether bovine follicles initiated to grow in vitro could be isolated from the cortical environment, and could undergo further development and 2) to evaluate the effect of… CONTINUE READING
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