Ontogeny of the opioidergic regulation of LH and prolactin secretion in lactating sow. I: failure of naloxone to antagonize suckling-induced changes in LH and prolactin secretion in early lactation, irrespective of pattern of administration.


The principal aim of this study was to investigate the ontogeny of an opioidergic mechanism mediating the suckling-induced inhibition of LH secretion during lactation in sows. In contrast to an increase in LH secretion in response to naloxone treatment on days 10 and 11 of lactation (P < 0.05), a single injection of 2 mg naloxone kg-1 at 39, 51, 63, or 75 h… (More)


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