Ontogeny of the kidney and renal developmental markers in the rhesus monkey (Macaca mulatta).

@article{Batchelder2010OntogenyOT,
  title={Ontogeny of the kidney and renal developmental markers in the rhesus monkey (Macaca mulatta).},
  author={Cynthia A. Batchelder and C. Chang I. Lee and Michele L. Martinez and Alice F. Tarantal},
  journal={Anatomical record},
  year={2010},
  volume={293 11},
  pages={1971-83}
}
Nonhuman primates share many developmental similarities with humans, thus they provide an important preclinical model for understanding the ontogeny of biomarkers of kidney development and assessing new cell-based therapies to treat human disease. To identify morphological and developmental changes in protein and RNA expression patterns during nephrogenesis, immunohistochemistry and quantitative real-time PCR were used to assess temporal and spatial expression of WT1, Pax2, Nestin, Synaptopodin… CONTINUE READING