Ontogeny of the circadian rhythm of cortisol in sheep.

  title={Ontogeny of the circadian rhythm of cortisol in sheep.},
  author={V{\'i}ctor H. Parraguez and Marta Vergara and Raquel Riquelme and R Raimann and An{\'i}bal J. Llanos and Mar{\'i}a Ser{\'o}n-Ferr{\'e}},
  journal={Biology of reproduction},
  volume={40 6},
In this work we investigated the ontogeny of the rhythm of plasma cortisol in sheep. Plasma cortisol was measured by radioimmunoassay in blood samples obtained every 1 or 2 h, for periods of 24 or 48 h, in 13 fetal sheep (124-140 days of gestation; 130.6 +/- 1.5, mean +/- SE) and in 23 newborn (5-39 days of age). To this end, indwelling polyvinyl catheters were implanted into the femoral artery and vein in all animals. The presence of rhythm was determined by Cosinor Analysis. Newborns were… CONTINUE READING