Ontogeny of the F8Famide-like (morphine-modulating) peptides in the central nervous system of rats.

@article{Kivipelto1991OntogenyOT,
  title={Ontogeny of the F8Famide-like (morphine-modulating) peptides in the central nervous system of rats.},
  author={Leena Kivipelto and Joel Allen Rubenstein and Ha Yung Yang and Pertti Panula},
  journal={The Journal of comparative neurology},
  year={1991},
  volume={304 1},
  pages={14-33}
}
FLFQPQRF-NH2 (F8Famide; FMRFamide-like peptide; morphine-modulating peptide) is a peptide isolated from bovine brain. It has some opiate analgesia modulating effects. In an adult rat central nervous system, F8Famide-like immunoreactivity is found in high concentrations in the posterior pituitary, hypothalamus, pons, medulla, and dorsal spinal cord. By using immunohistochemistry and radioimmunoassay, we studied the development of the F8Famide-immunoreactive system in the rat central nervous… CONTINUE READING