Ontogeny of prolactin releasing and inhibiting activities in the posterior pituitary of male rats.

@article{Laudon1989OntogenyOP,
  title={Ontogeny of prolactin releasing and inhibiting activities in the posterior pituitary of male rats.},
  author={Moshe Laudon and James F. Hyde and Nira Ben-Jonathan},
  journal={Neuroendocrinology},
  year={1989},
  volume={50 6},
  pages={644-9}
}
Plasma PRL levels in male rats are highest during the peripubertal period. We previously reported that the posterior pituitary (PP) contains a potent PRL-releasing factor (PRF), a trypsin-insensitive small peptide which is distinct from known PRL secretagogues. The objectives were to determine the ontogeny of PRF activity in the PP as well as age-related alterations in anterior pituitary responsiveness to PRF. We also explored if the PP contains a nondopaminergic PRL-inhibiting factor (PIF… CONTINUE READING