Ontogeny and the effect of aging on pancreatic polypeptide and peptide YY
@article{Sandstrm2002OntogenyAT, title={Ontogeny and the effect of aging on pancreatic polypeptide and peptide YY}, author={Olof Sandstr{\"o}m and Magdy El-Salhy}, journal={Peptides}, year={2002}, volume={23}, pages={263-267} }
12 Citations
PYY in the expanding pancreatic epithelium
- BiologyEndocrine
- 2007
The data suggest that PYY may be a mediator of islet cell development, as well as a cofactor for growth factor responses, not only during fetal pancreas formation but also during regeneration in adult animals.
Molecular cloning, tissue and embryonic development expression, and appetite regulatory effect of pancreatic peptide Y in Coilia nasus
- BiologyFisheries Science
- 2015
A potential role for PY in appetite regulation is revealed and provides a basis for further study of Py in C. nasus, suggesting a potential relationship between food intake and the expression of PY.
Pancreatic PYY but not PPY expression is responsive to short-term nutritional state and the pancreas constitutes the major site of PYY mRNA expression in chickens
- BiologyGeneral and comparative endocrinology
- 2017
Reg IV is differently expressed in enteroendocrine cells of human small intestine and colon
- Biology, MedicineRegulatory Peptides
- 2013
The role of peptide YY in gastrointestinal diseases and disorders
- MedicineInternational journal of molecular medicine
- 2013
Investigating changes in PYY in gastrointestinal diseases/disorders could be beneficial in clinical practice, where a receptor agonist or an antagonist can be used as a drug, depending on the condition.
The Gastrointestinal System and Aging
- Medicine
- 2012
The chapter discusses morphological and physiological changes with age in the GI system and provides clinical applications where relevant.
Molecular cloning, expression analysis, and potential food intake attenuation effect of peptide YY in grass carp (Ctenopharyngodon idellus).
- BiologyGeneral and comparative endocrinology
- 2013
References
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Results suggest that PYY-positive endocrine cells may represent precursors for mature islet cells, consistent with a precursor role of triple-positive (insulin+glucagon+PYY) cells.
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The difference between PYY-and PP-immunoreactive cells in the distribution, frequency and ontogeny provide further evidence that PYY and PP occur in two independent cell types.
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The hormone peptide YY is produced by endocrine cells in the pancreas, ileum and colon. We have previously shown that peptide YY is coexpressed in all four islet cell types in the murine pancreas…
Expression of peptide YY in all four islet cell types in the developing mouse pancreas suggests a common peptide YY-producing progenitor.
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The use of conditions that distinguish peptide YY from the related peptides, pancreatic polypeptide and neuropeptid Y, as well as the ability of the peptideYY gene to direct expression of a reporter gene in islets of transgenic mice, establishes expression of peptide yY in the earliest pancreatic endocrine cells.
ONTOGENY OF POLYPEPTIDE YY (PYY) CELLS IN THE GUT OF CHICKEN: AN IMMUNOCYTOCHEMICAL STUDY
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The occurrence of polypeptide YY (PYY) immunoreactive cells was investigated in various parts of the alimentary tract of chick embryos from 60 h to 18 days of incubation and of chicken from l to 4…
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A complex and specific regulation of posttranslational processing during maturation for these two peptides is revealed and it is revealed that only GLP-1-(7-36) amide is produced during intestinal development.
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The trophic effects of PYY were dose related, peptide specific, and independent of species and sex, hypothesize that PYY plays an important role in intestinal development and dietary adaptation in rats and mice.